Ethical and Social Challenges of Genomic and Precision Medicine

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Opleiderscore: starstarstarstar_halfstar_border 7,2 Coursera (CC) heeft een gemiddelde beoordeling van 7,2 (uit 6 ervaringen)

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Beschrijving

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About this course: Please note: This course was developed in 2014. This course is not actively moderated by course instructors, please use the course forums to collaborate with other learners. Knowledge linking genomics to health and disease is rapidly expanding. Translation of this knowledge into clinical and public health practice offers promising opportunities but also raises a host of ethical, legal, social, and policy questions. Using case examples, this inter-disciplinary course will explore the challenges of genomic and precision medicine. This seven week, inter-disciplinary course provides an introduction to ethical, legal, social, and policy issues that arise in the translation…

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When you enroll for courses through Coursera you get to choose for a paid plan or for a free plan

  • Free plan: No certicification and/or audit only. You will have access to all course materials except graded items.
  • Paid plan: Commit to earning a Certificate—it's a trusted, shareable way to showcase your new skills.

About this course: Please note: This course was developed in 2014. This course is not actively moderated by course instructors, please use the course forums to collaborate with other learners. Knowledge linking genomics to health and disease is rapidly expanding. Translation of this knowledge into clinical and public health practice offers promising opportunities but also raises a host of ethical, legal, social, and policy questions. Using case examples, this inter-disciplinary course will explore the challenges of genomic and precision medicine. This seven week, inter-disciplinary course provides an introduction to ethical, legal, social, and policy issues that arise in the translation of genomic knowledge into medical and public health practice. It considers challenges in health related and reproductive testing/screening focusing on six specific areas: • Pre‐conception genetic diagnosis, and prenatal testing/screening • Newborn screening • Use of genomic sequencing technologies to diagnose and predict disease • Targeting genomic testing/screening by race/ethnicity • Direct‐to‐consumer genomic testing/screening • Use of “big data” for genomic research and genomic translation Course Objectives 1. Critique the promise of genomics and precision medicine for improving health outcomes for individuals and populations. 2. Through analysis of key cases, demonstrate an understanding of the ethical, legal, social, and policy (ELSI) challenges that accompany the translation of new genomic knowledge into clinical medicine and public health practice. 3. Apply a critical analysis of ELSI concerns to your professional practice (if relevant), your interest as a potential user of genomic knowledge, and as a citizen with a responsibility to shape health policy.

Who is this class for: This course is directed toward learners with an interest in bioethics, genetics, medical genetics, genetic counseling, public health, as well as members of the broader public with an interest in the ethical, legal, social, and policy issues raised by the new science of genomics.

Created by:  University of California, San Francisco
  • Taught by:  Wylie Burke, MD, PhD, Professor, Department of Bioethics and Humanities, University of Washington

    2013-14 Presidential Chair, University of California, San Francisco
  • Taught by:  Barbara A. Koenig, PhD, Professor of Medical Anthropology & Bioethics

    Dept. of Social & Behavioral Sciences, Institute for Health & Aging, & Dept. of Anthropology, History, and Social Medicine
  • Taught by:  Julie N. Harris-Wai, Ph.D., MPH, Assistant Adjunct Professor

    Department of Behavioral and Social Sciences
Language English How To Pass Pass all graded assignments to complete the course. User Ratings 4.5 stars Average User Rating 4.5See what learners said Coursework

Each course is like an interactive textbook, featuring pre-recorded videos, quizzes and projects.

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University of California, San Francisco The University of California, San Francisco, is dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. UC San Francisco is the only campus in the University of California system dedicated exclusively to the health sciences. UCSF's innovative, collaborative approaches for health care, research and education span disciplines across the health sciences and make it a world leader in scientific discovery and its translation into improved health.

Syllabus


WEEK 1


Week 1
Introduction to Genetics in Medicine and Public Health, Genetics as a Tool in Cancer Prevention, and Genetic Screening.


4 videos, 2 readings expand


  1. Video: Week 1 Introduction
  2. Video: Introduction: Genetics in Medicine and Public Health
  3. Video: Cancer Genetics: Genetics as a Tool in Cancer Prevention
  4. Video: Genetic Screening to Improve Health: Newborns and Beyond
  5. Reading: Deflating the Genomic Bubble
  6. Reading: PowerPoint Slides

Graded: Quiz: Week 1

WEEK 2


Week 2
Reproductive Genetics


3 videos, 3 readings expand


  1. Video: Week 2 Introduction
  2. Video: Reproductive Genetics: Carrier Screening
  3. Video: Reproductive Genetics: Screening for Trisomy 21
  4. Reading: Reproductive Genetics
  5. Reading: PowerPoint Slides
  6. Reading: Self Assessment

Graded: Week 2 Quiz

WEEK 3


Week 3
Screening


5 videos, 2 readings expand


  1. Video: Week 3 Introduction
  2. Video: Screening: Newborn Screening Programs
  3. Video: Screening: Challenges in Achieving Benefit
  4. Video: Screening: Screening Adults – Questions Coming our Way
  5. Video: Cancer Genetics: "Incidental" Findings in Research and Clinical Care
  6. Reading: Screening
  7. Reading: PowerPoint Slides

Graded: Week 3 Quiz

WEEK 4


Week 4
Genetic Technology in the Prediction and Diagnosis of Disease


4 videos, 3 readings expand


  1. Video: Week 4 Introduction
  2. Video: Growing Genetic Knowledge in the Early 20th Century
  3. Video: Dramatic Growth and Intersection of Genetics and Other Biomedical Sciences
  4. Video: What New Opportunities Will Precision Medicine Bring?
  5. Reading: Genetic Technology
  6. Reading: PowerPoint Slides
  7. Reading: Self Assessment

Graded: Week 4 Quiz

WEEK 5


Week 5
Race and Genetics


3 videos, 2 readings expand


  1. Video: Week 5 Introduction
  2. Video: History of Race and Racial Categories
  3. Video: Race and Efforts to Eliminate Health Disparities
  4. Reading: Race and Genetics
  5. Reading: PowerPoint slides

Graded: Week 5 Quiz

WEEK 6


Week 6
Direct to Consumer Testing


3 videos, 2 readings expand


  1. Video: Week 6 Introduction
  2. Video: Direct-to-Consumer Genomics: A Personal Journey
  3. Video: Debate About Direct to Consumer Testing
  4. Reading: Direct to Consumer Testing
  5. Reading: Self Assessment

Graded: Week 6 Quiz

WEEK 7


Week 7
Where Do We Go From Here?


4 videos, 2 readings expand


  1. Video: Week 7 Introduction: Where Do We Go From Here?
  2. Video: How Can Genomic Information Be Used for Benefit?
  3. Video: The Problem of Limited Predictive Value
  4. Video: Do We Need Big Data?
  5. Reading: Genomic Analysis Are the Future of Medicine
  6. Reading: PowerPoint slides

Graded: Week 7 Quiz

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